Transforming growth factor-betas (TGF betas) are multifunctional peptides that regulate growth and differentiation in a variety of cells. The TGF-beta family of growth modulators play critical roles in tissue development and maintenance. TGF-beta isoforms (TGF-beta 1, -beta 2 and -beta 3) have overlapping yet distinct biological actions and target cell specificities, both in developing and adult tissues TGF beta 3 is a new isoform of the TGF beta superfamily and is presumed to play an important role in wound repair and scarring. TGF-beta 3 is believed to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant Human TGF-b 3 is a disulfide-linked homodimer. Animal Free: This product is produced with no animal-derived raw products, animal free equipment and animal free protocols.
Peptides & proteins
TGF-β3 (AF) (0.25 mg/ml)
Produced using animal free raw components and processes, in a non-mammalian system. Ideal for researchers concerned about the risks and effects of contaminating viruses, prions and trace growth factors from FBS and animal-derived ingredients used in standard recombinant protein production techniques. Endotoxin levels are less than 1.0 EU per ug protein via LAL. Bioactivity is comparable to recombinant protein produced in traditional techniques.