ProTx-I (Cy5)
Supplier:
Catalogue number:
PTF001-50010
Size:
5 x 10 µg
Product is available in:
Cy5-ProTx-I is a Cy5 fluorescently labeled peptide. Protoxin I (ProTx-I; β-theraphotoxin-Tp1a) is a toxin that was originally isolated from the venom of Thrixopelma pruriens (Peruvian green velvet tarantula). This toxin reversibly inhibits the tetrodotoxin (TTX)-resistant channel Nav1.8 (IC50 = 27 nM) and TTX sensitive Nav channels such Nav1.2, Nav1.5 and Nav1.7 with IC50 values between 50 and 100 nM. Furthermore, ProTx-I shifts the voltage dependence activity of T-type Cav3.1 channels (IC50= 50 nM) without affecting the voltage dependence of inactivation.
Product Type:
Peptides & proteins
Alternative Names:
Protoxin I; ProTx 1