Iberiotoxin (IbTx)
Supplier:
Catalogue number:
12IBX001-05100
Size:
5 x 10 µg
Product is available in:
Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to study specifically Maxi-K channels.
- Applications:TARGET CLASS: Potassium channel; TARGET: BK; ACTION: Blocker
Product Type:
Peptides & proteins
CAS Number:
129203-60-7
Alternative Names:
IbTx
Limit of Detection:
4230.8 Da
Storage Temperature:
RT
Additional Information:
AA SEQUENCE: pGlu-Phe-Thr-Asp-Val-Asp-Cys-Ser-Val-Ser-Lys-GIu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-GIn-OH; DISULFIDE BRIDGES: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35; SOURCE: Synthetic; PURITY: > 95%