LIF (AF)

Mouse Leukemia Inhibitory Factor (LIF) is member of the IL-6 family and is made by a variety of tissues. LIF signals through receptors gp190 (LIFR) and gp130 to activate STAT3 which ultimately promotes mouse embryonic stem cell self-renewal and pluripotentcy of long term cultures. This activity is similar to that attributed to FGF-basic (FGF-2) for human embryonic stem cells. Recombinant mouse LIF is a non-glycosylated protein. Animal Free: This product is produced with no animal-derived raw products, animal free equipment and animal free protocols.