ML418
Supplier:
Catalogue number:
10-4652-02
Size:
25 mg
Product is available in:
Kir7.1/6.2 blocker / ML418 is a blocker of the inward rectifier potassium channels Kir7.1 (IC50 = 310nM) and Kir6.2 (equipotent) with metabolic and pharmacokinetic parameters suitable for in vivo research.1 Greater than 23-fold selectivity over Kir1.1, Kir2.1, Kir2.2, Kir2.3, Kir4.1.
Product Type:
Biochemicals & reagents
CAS Number:
1928763-08-9
Reference:
1) Swale et al. (2016), ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels; ACS Chem. Neurosci. 7 1013
Storage Temperature:
-20°C
Additional Information:
TARGET: Ion channel -- PATHWAY: Cation channel