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Ivabradine HCl

Supplier:
Catalogue number:
10-2694-01
Size:
10 mg
Product is available in:
  • USA
  • Canada
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Heart failure / unstable angina treatment / Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2

Product Type:

Biochemicals & reagents

CAS Number:

148849-67-6

Reference:

Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2

Storage Temperature:

-20°C

Additional Information:

TARGET: Ion channel -- PATHWAY: Calcium signaling -- DISEASE AREA: Heart disease