Genistin
Genistein glycoside / A novel selective inhibitor of terminal deoxyribonucleotidyl-transferase1. Disrupts cell cycle and induces apoptosis in human ovarian cancer SK-OV-3 cells2. Inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells3.
Biochemicals & reagents
529-59-9
1) Uchiyama et al. (2005), Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin; Biochim. Biophys. Acta, 1725 298 2) Choi et al. (2007), Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells; Life Sci, 80 1403 3) Russo et al. (2006), Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells J. Nutr. Biochem., 17 103
-20°C
TARGET: DNA -- PATHWAY: Cell cycle; Apoptosis inducer; DNA damage -- RESEARCH AREA: Cell death -- DISEASE AREA: Cancer