XAV-939
Supplier:
Catalogue number:
10-1186-01
Size:
5 mg
Product is available in:
Tankyrase inhibitor, Cardiomyogenesis inducer / Tankyrase inhibitor (IC50=11 and 4 nM for TNKS1 and 2 respectively). Antagonizes wnt signaling via stimulation of ß-catenin degradation and stabilization of actin.1 Robustly induces cardiomyogenesis of stem cells.2 Cell Permeable
Product Type:
Biochemicals & reagents
CAS Number:
284028-89-3
Reference:
1) Huang et al. (2009), Tankyrase inhibition stabilizes axin and antagonizes Wnt signaling; Nature, 46 614. / 2) Wang et al. (2011), Cardiac induction of embryonic stem cells by a small molecule inhibitor of Wnt/ß-catenin signaling; Chem. Biol., 6 192
Storage Temperature:
RT
Additional Information:
TARGET: Cytoskeleton -- PATHWAY: Wnt -- RESEARCH AREA: Stem cells