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Etoposide

Etoposide
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Size: 100 mg
$45.00
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Catalogue number:
10-1123-01
Name:
Etoposide
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Topoisomerase II inhibitor

Data sheet:

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Applications:


Topoisomerase II inhibitor

Product Type:
Biochemicals & reagents
CAS Number:
33419-42-0
Storage Temp:
Room Temperature
Molecular Weight:
588.56
Reference:
1) Hande (1998) Etoposide: four decades of development of a topoisomerase II inhibitor:; Eur. J. Cancer 34, 1514 / 2) Smith et.al. (1994) Etoposide-induced cell cycle delay and arrest-dependent modulation of DNA topoisomerase II in small-cell lung cancer cells. Br J Cancer. 70 914
Additional Information:
Etoposide (33419-42-0) is a chemotherapeutic agent that forms a ternary complex with DNA and topoisomerase II, preventing re-ligation of DNA strands causing DNA cleavage. Etoposide blocks the cell cycle in S-phase and G2-phase.