IL-7, human recombinant
Interleukin-7 (IL-7), which is constitutively produced particularly by stromal cells from the bone marrow and thymus, plays a crucial role in T cell homeostasis. This cytokine is implicated in thymopoiesis since it sustains thymocyte proliferation and survival. It regulates peripheral naive T cell survival by modulating the expression of the anti-apoptotic molecule Bcl-2, and sustains peripheral T cell expansion in response to antigenic stimulation. Recombinant Human IL-7 is a single, non-glycosylated polypeptide chain.
Peptides & proteins
Lymphopoietin 1 (LP-1), pre-B cell Factor
-20°C
NAME: Interleukin-7; ACCESSION/UNIPROT#: P13232; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM Aceitic acid. Reconstitute in sterile 10 mM Aceitic acid at 0.1 mg/mL.; TESTING: Mouse 2E8 cell proliferation with an acceptance criteria of 1 ng/mL (ED50), 1 x 10^6 units/mg.; #AA: 153; SEQUENCE: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH