BDNF, human recombinant
BDNF is a member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Some protein domains of BDNF are identical with those of NGF and another neurotrophic factor, designated NT-3 (neurotrophin-3). Polyclonal antibodies raised against murine NGF have been shown to cross-react with both NT-3 and BDNF. Recombinant Human BDNF is a homodimer, non-glycosylated, polypeptide chain.
Peptides & proteins
-20°C
NAME: Brain Derived Neurotrophic Factor; ACCESSION/UNIPROT#: P23560; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile filtered solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: C6 cell proliferation with an acceptance criteria of 2 ug/mL (ED50), 5.0 x 10^2 units/mg.; #AA: 120; SEQUENCE: MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR