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StemRegenin 1

Catalogue number:
SM98-5
Size:
5 mg
Product is available in:
  • USA
  • Canada
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StemRegenin 1 is an AhR inhibitor. StemRegenin 1 induces CD34+ cell expansion by binding and antagonizing AhR. StemRegenin 1 treatment accelerates the proliferation of CD34+ cells. Sequential co-culture with BMP-4, PGE2, and StemRegenin 1 leads to robust Macaca nemestrina iPSC hematopoietic progenitor cell formation. Culture of mPB CD34+ cells with cytokines plus StemRegenin 1 increases the number of CD34+, CD133+ and CD90+ hematopoietic stem and progenitor cell populations compared to control cells. StemRegenin 1 promotes human plasmacytoid and myeloid dendritic cell development from CD34+ hematopoietic progenitor cells.

Product Type:

Peptides & proteins

CAS Number:

1227633-49-9

Alternative Names:

SR1, 4-[2-[[2-benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]-phenol

Range:

1) Gao, H., et al. 2012. J Biol Chem. 287(35): 29979-29987. PMID: 22791709; 2) Gori, JL., et al. 2012. Blood. 120(13): e35-44. PMID: 22898598; 3) Thordardottir, S., et al. 2014. Stem Cells Dev. 23(9): 955-967. PMID: 24325394

Limit of Detection:

429.54

Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt