www.mayflowerbio.com
Sales & Support: 314-485-5210

*

Sorafenib

Catalogue number:
SM95-500
Size:
500 mg
Product is available in:
  • USA
  • Canada
$267.00 Shipping is calculated in checkout

Sorafenib is a multikinase inhibitor with activity against Raf kinase and several receptor tyrosine kinases, including vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), FLT3, Ret, and c-Kit. It suppresses ERK phosphorylation. It also induces the phosphorylation of PKA. Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and signaling-independent mechanisms).

Product Type:

Peptides & proteins

CAS Number:

284461-73-0

Alternative Names:

Bay 43-9006, Nexavar, 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-Nmethyl-pyridine-2-carboxamide