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XAV939

Catalogue number:
SM38-2
Size:
2 mg
Product is available in:
  • USA
  • Canada
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XAV939 is a beta-catenin-mediated transcription inhibitor of selective Wnt pathway. Alternatively, it acts as axin stabilizing agent for the inhibition of TNKS1 and TNKS2. XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.

Product Type:

Peptides & proteins

CAS Number:

284028-89-3

Alternative Names:

XAV 939, XAV-939, 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one

Range:

1) Smith, S., et al. 1998. Science. 282(5393): 1484-1487. PMID: 9822378; 2) Huang, SM., et al. 2009. Nature. 461(7264): 614-620. PMID: 19759537

Limit of Detection:

312.31

Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt