www.mayflowerbio.com
Sales & Support: 314-485-5210

*

Trichostatin A 

Catalogue number:
SM38-10
Size:
10 mg
Product is available in:
  • USA
  • Canada
$175.00 Shipping is calculated in checkout

XAV939 is a beta-catenin-mediated transcription inhibitor of selective Wnt pathway. Alternatively, it acts as axin stabilizing agent for the inhibition of TNKS1 and TNKS2. XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.

Product Type:

Peptides & proteins

CAS Number:

284028-89-3

Alternative Names:

XAV 939, XAV-939, 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one

Range:

1) Laping, NJ., et al. 2002. Mol Pharmacol. 62(1): 58-64. PMID: 12065755; 2) Hjelmeland, MD., et al. 2004. Mol Cancer Ther. 3(6): 737-745. PMID: 15210860; 3) Lei, Y. and Schaffer, DV. 2013. Proc Natl Acad Sci U S A. 110(52): E5039-5048. PMID: 24248365

Limit of Detection:

384.39

Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt