www.mayflowerbio.com
Sales & Support: 314-485-5210

*

TG101348

Catalogue number:
SM103-5
Size:
5 mg
Product is available in:
  • USA
  • Canada
$165.00 Shipping is calculated in checkout

TG101348 is a selective small-molecule Janus kinase 2 (JAK2) inhibitor.TG101348 also inhibits FLT3 and RET. TG101348 exhibits promising pharmacokinetic profiles. TG101348 inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less inhibitory effect on the self-renewal of CD34+ hematopoietic progenitors.

Product Type:

Peptides & proteins

CAS Number:

936091-26-8

Alternative Names:

SAR302503, SAR302503, N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin4-ylamino)benzenesulfonamide

Range:

1) Wernig, G., et al. 2008. Cancer Cell. 13(4): 311-320. PMID: 18394554; 2) Ye, Z., et al. 2014. Stem Cells. 32(1): 269-278. PMID: 24105986; 3) Mullally A., et al. 2010. Cancer Cell. 17(6): 584-596. PMID: 20541703

Limit of Detection:

524.68

Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt