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Dorsomorphin Dihydrochloride

Catalogue number:
2 mg
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Dorsomorphin is a BMP pathway inhibitor, which inhibits bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK 6). Dorsomorphin, also named as AMPK Inhibitor, has also been shown to play role as a potent and selective inhibitor of AMPK, induced by AICAR and metformin. Dorsomorphin promotes cardiomyogenesis in mouse embryonic stem cells (ESC) and induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.

Product Type:

Peptides & proteins

CAS Number:


Alternative Names:

AMPK Inhibitor I, BML-275, BMP Inhibitor I, Compound C, 6-[4-(2-Piperidin-1-yl-ethoxy)-phenyl)]-3-pyridin-4-yl-pyrrazolo[1,5-a]-pyrimidine dihydrochloride