Interleukin-5 (IL-5) is a hematopoietic growth factor expressed in Th2, mast cells and eosinophils. IL-5 acts through its receptor, the IL-5 receptor (IL-5R) and is involved in B cell growth and eosinophil activation. Human and mouse IL-5 are cross-reactive. Recombinant human IL-5 is a non-glycosilated homodimer containing two 116 amino acid chains and with a molecular weight of 26.6 kDa.
Peptides & proteins
B-cell differentiation factor I, Eosinophil differentiation factor, TFR
NAME: Interleukin-5; ACCESSION/UNIPROT#: P05113; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium glycinate, pH 8.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: TF-1 cell proliferation with an acceptance criteria of 250 pg/mL (ED50), 4 x 10^6 units/mg.; #AA: 232; SEQUENCE: MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES