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ρ-Da1a (AdTx1)

Catalogue number:
ADT001-00010
Size:
10 µg
Product is available in:
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AdTx1 (rho-Da1a – ρ-Da1a) is a 65 amino-acid peptide originally isolated from the venom of the green mamba, an African snake (Dendroaspis angusticep). AdTx1 is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. AdTx1 has subnanomolar affinity (K(i)= 0.35 nM) and high specificity for the human alpha(1A)-adrenoceptor subtype and is 1000 times more potent on this subtype than on other adrenoceptor subtypes. AdTx1 is a potent relaxant of smooth muscles.

  • Applications:TARGET CLASS: GPCR; TARGET: a1-adrenoreceptor; ACTION: Blocker
Product Type:

Peptides & proteins

Alternative Names:

AdTx1

Limit of Detection:

7283.29 Da

Storage Temperature:

RT

Additional Information:

AA SEQUENCE: LTC3VTSKSIFGITTEDC17PDGQNLC24FKRRHYVVPKIYDSTRGC42AATC46PIPENYDSIHC57C58KTDKC63NE; DISULFIDE BONDS: Cys3-Cys24, Cys17-Cys42, Cys46-Cys57, Cys58-Cys63; SOURCE: synthetic; PURITY: > 98%

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