Recombinant Hla (tag free)

Staphylococcus aureus alpha hemolysin (Hla), also known as alpha toxin (α-toxin), is expressed in E. coli as a recombinant protein without TAG. The theoretical molecular weight of the protein is approximately 33 kDa.

Applications:

ELISA, WB
Hla is produced by S. aureus and is a major cytotoxic agent. It is expressed as a monomer that binds to the membrane of susceptible cells. Subunits then oligomerize to form heptameric rings with a central pore through which cellular contents leak. The mod