GSK-690693 HCl
Supplier:
Catalogue number:
10-1310-01
Size:
5 mg
Product is available in:
AKT inhibitor / A novel ATP-competitive pan-specific Akt kinase inhibitor. (IC50’s=2, 13, 9 nM for Akt1, 2 and 3 respectively) Antitumor activity. Active in vivo. Induces hyperglycemia. Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
937174-76-0
Reference:
1) Rhodes et al. (2008), Characterization of an Akt kinase inhibitor with potent pharmacodynamics and antitumor activity; Cancer Res., 68 2366 2) Crouthamel et al. (2009), Mechanism and management of AKT inhibitor-induced hyperglycemia; Clin. Cancer Res., 15 217
Storage Temperature:
-20°C
Additional Information:
TARGET: Kinase -- PATHWAY: AKT -- DISEASE AREA: Diabetes; Cancer