Nilotinib
Supplier:
Catalogue number:
10-2152-02
Size:
50 mg
Product is available in:
BCR-ABL inhibitor / A novel, selective BCR-ABL inhibitor. More potent than imatinib against wild-type BCR-ABL (IC50 < 30 nM)1. Induces apoptosis2.
Product Type:
Biochemicals & reagents
CAS Number:
641571-10-0
Alternative Names:
AMN-107
Reference:
1) Weisberg et al. (2006), AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL; Br. J. Cancer, 94 1765 2) Verstovsek et al. (2006), Activity of AMN107, a novel aminopyrimidine tyrosine kinase inhibitor, against human FIP1L1-PDGFR-alpha-expressing cells; Leuk. Res., 30 1499
Storage Temperature:
-20°C
Additional Information:
TARGET: Kinase -- PATHWAY: Apoptosis inducer; Autophagy -- RESEARCH AREA: Cell death -- DISEASE AREA: Cancer