AM-404
Supplier:
Catalogue number:
10-2008-01
Size:
10 mg
Product is available in:
Anandamide transport inhibitor / Inhibits anandamide transport (IC50 = 1 µM) without inhibiting anandamide amidase or activating cannabinoid receptors.1,2 Vanilloid receptors are activated by AM-404.3 Active in vivo.1
Product Type:
Biochemicals & reagents
CAS Number:
198022-70-7
Reference:
1) Calignano et al. (1997), Potentiation of anandamide hypotension by the transport inhibitor AM404; Eur. J. Pharmacol., 337 R1 2) Beltramo et al. (1997), Functional role of high-affinity anandamide transport, as revealed by selective inhibition; Science, 277 1094 3) Zygmunt et al. (2000), The anandamide inhibitor AM404 activates vanilloid receptors: Eur. J. Pharmacol. 396 39
Storage Temperature:
-20°C
Additional Information:
TARGET: GPCR -- PATHWAY: Cannabinoid receptor