AZD-2098
Supplier:
Catalogue number:
10-4262-01
Size:
5 mg
Product is available in:
CCR4 antagonist / Potent, orally bioavailable antagonist of CCR4 (pIC50 = 7.8(h), 8.0(r), 8.0(m), 7.6(d)).1 Inactive at CXCR1/2, CCR1, CCR2b, CCR5, CCR7, and CCR8 @ 10 µM.
Product Type:
Biochemicals & reagents
CAS Number:
566203-88-1
Reference:
Kindon et al. (2017), Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists; ACS Med. Chem. Lett. 8 981
Storage Temperature:
-20°C
Additional Information:
TARGET: GPCR -- PATHWAY: Cytokine; Calcium signaling -- RESEARCH AREA: Immunology -- DISEASE AREA: Inflammation; Cancer