Cyclopamine
Supplier:
Catalogue number:
10-1082-01
Size:
5 mg
Product is available in:
Hedgehog signaling inhibitor / Naturally occurring steroidal alkaloid with teratogenic activity. Blocks sonic hedgehog signaling by binding to smoothened. Antitumor activity. Cell Permeable.
Product Type:
Biochemicals & reagents
CAS Number:
4449-51-8
Reference:
1) Watkins et al. (2003), Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer; Nature, 422 313
Storage Temperature:
-20°C
Additional Information:
TARGET: GPCR -- PATHWAY: Hedgehog; Cell cycle; Apoptosis inducer -- RESEARCH AREA: Cell death; Stem cells -- DISEASE AREA: Cancer