Epothilone B
Supplier:
Catalogue number:
10-2133-01
Size:
1 mg
Product is available in:
Microtubule stabilizing agent / Induces microtubule polymerization. Causes cell cycle arrest at the G2-M transition (EC50 = 32 nM for HeLa cells). Induces apoptosis. Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
152044-54-7
Alternative Names:
EPO-906; EpoBI; Patupilone
Reference:
1) Goodin et al. (2004), Epothilones: mechanism of action and biologic activity; J. Clin. Oncol., 22 2015 / 2) Bollag et al. (1995), Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action; Cancer Res., 55 2325
Storage Temperature:
-20°C
Additional Information:
TARGET: Cytoskeleton -- PATHWAY: Apoptosis inducer; Cell cycle -- RESEARCH AREA: Cell death