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ω-conotoxins SO-3

ω-conotoxins SO-3
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Size: 0.1 mg
$292.00
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Catalogue number:
08CON013-00100
Name:
ω-conotoxins SO-3
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ω-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). This peptide selectively targets N-type voltage-sensitive calcium channels. It has no effect on R-type calcium currents, voltage-sensitive sodium currents, delayed rectifier potassium currents and transient outward potassium currents. It displays an analgesic potency similar to MVIIA in a range of acute and chronic pain models in rodents, but has less adverse effects compared with identical dosages of MVIIA injected intrathecally.

Product Type:
Peptides & proteins
Alternative Names:
omega conotoxin SO3
Storage Temp:
RT
Molecular Weight:
2567.07 Da
Reference:
Wen, L., et al. (2005) Br J Pharmaco; Dai, Q., et al. (2003) J Nat Prod; Li, Z., et al (2003) Brain Res