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SNX482

SNX482
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Size: 0.1 mg
$350.00
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Catalogue number:
08SNX001-0100
Name:
SNX482
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SNX-482 has been isolated from the venom of the Spider Hysterocrates gigas (African tarantula). This toxin modulates the R-type current associated with the class α1E calcium channel (Cav2.3 from the CACNA1E gene). SNX-482 antagonizes channel activation by inducing a depolarizing shift in the activation potential, thus preventing the channel from undergoing normal membrane depolarization. SNX-482 acts rapidly and maintains its effect.

Product Type:
Peptides & proteins
CAS Number:
203460-30-4
Storage Temp:
RT
Molecular Weight:
4496.42 Da
Reference:
Bourinet, E., et al. (2001) Biophys; Newcomb, R., et al. (1998) Biochemistry