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Nafamostat mesylate

Supplier:
Catalogue number:
10-1089-01
Size:
10 mg
Product is available in:
  • USA
  • Canada
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Protease inhibitor: Serine proteases. Targets viral cell entry via inhibition of ACE2/TMPRSS2. Gordon et al. bioRxiv, Mar 23 2020, https://doi.org/10.1101/2020.03.22.002386; Wang et al. Cell Res 30:269–271, Feb 4 2020, https://doi.org/10.1038/s41422-020-0282-0; Guy et al. Science, 368 829-830 May 22 2020, https://doi.org/10.1126/science.abb9332.

  • Datasheet:   view or download
  • Applications:Approved drug (Japan) that could be repurposed
Product Type:

Biochemicals & reagents

CAS Number:

5668873

Range:

1) Han et al. (2019) Identification of nafamostat mesilate as an inhibitor of the fat mass and obesity-associated protein (FTO) demethylase; Chemico-Biological Interactions, 297 80

Limit of Detection:

347.38 ∙ 192.21

Storage Temperature:

Room Temperature

Additional Information:

Nafamostat mesylate is a potent and reversible serine protease inhibitor (IC50's range from 0.3 - 54.0 μM) which inhibits the demethylase activity of the fat mass and obesity-associated protein (FTO) (1).