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Imatinib mesylate

Catalogue number:
100 mg
Product is available in:
  • USA
  • Canada
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Kinase inhibitor: tyrosine kinases. Inhibits SARS-CoV and MERS-CoV in cells. Dyall et al. Antimicrob. Agents Chemother., 58:4885-4893 2014, https://doi.org/10.1128/aac.03036-14.

  • Datasheet:   view or download
  • Applications:Approved drug (U.S.); in COVID-19 clinical trials
Product Type:

Biochemicals & reagents

CAS Number:



1) Buchdunger, et al.(1996) Inhibition of the Abl Protein-Tyrosine Kinase in Vitro and in Vivo by a 2-Phenylpyrimidine Derivative; Cancer Res. 56, 100 / 2) Heinrich et al (2000) Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood 96 925.

Limit of Detection:

493.62 ∙ 96.11

Storage Temperature:


Additional Information:

Imatinib is a tyrosine kinase inhibitor specific for abl (IC50 = 0.038 µM) (1), for PDGF-R (IC50 = 0.3 µM) (1) and for c-kit (IC50 = 0.1 µM) (2). This compound is a clinically relevant anti-cancer drug approved for the treatment of chronic myelogenous leukemia, gastrointestinal stromal tumors as well as several other cancers.