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Verapamil HCl

Supplier:
Catalogue number:
10-1111-02
Size:
5 g
Product is available in:
  • USA
  • Canada
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Ion channel antagonist. Targets Multidrug resistance-associated protein 1 (MRP1), which interacts with SARS-CoV-2 Orf9c. Gordon et al. bioRxiv, Mar 23 2020, https://doi.org/10.1101/2020.03.22.002386; Si et al. bioRxiv, Apr 14 2020, https://doi.org/10.1101/2020.04.13.039917.

  • Datasheet:   view or download
  • Applications:Approved drug (U.S.) that could be repurposed
Product Type:

Biochemicals & reagents

CAS Number:

152-11-4

Range:

1) Brgden and Benfield (1996) Verapamil: a review of its pharmacological properties and therapeutic use in coronary artery disease Drugs 51 792 / 2) Safa et al. (1987) Identification of the multidrug resistance-related membrane plycoprotein as an acceptor for calcium channel blockers J. Biol.Chem. 262 7884

Limit of Detection:

491.06

Storage Temperature:

Room Temperature

Additional Information:

Verapamil is a clinically useful L-type calcium channel blocker (1) and it is also used as an inhibitor of drug efflux pump proteins (2).