Bromosporine
Supplier:
Catalogue number:
10-4030-02
Size:
25 mg
Product is available in:
Bromodomain inhibitor. SARS-CoV-2 transmembrane protein E binds to the bromodomain-containing proteins BRD2 and BRD4.
- Datasheet: view or download
- Applications:Tool compound
Product Type:
Biochemicals & reagents
CAS Number:
1619994-69-2
Range:
1) Picaud et al. (2016), Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia; Sci.Adv. 2 e1600760 2) Pan et al. (2017), The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells; Oncotarget 8 94104
Limit of Detection:
404.44
Storage Temperature:
-20°C
Additional Information:
Bromosporine is a potent pan-Bromodomain (BRD) inhibitor (1) and it was able to reactivate HIV-1 replication in different latency models (2).