Oseltamivir phosphate
Supplier:
Catalogue number:
10-4483-02
Size:
250 mg
Product is available in:
Antiviral (influenza); Neuraminidase inhibitor. In silico, binds strongly to key SARS-CoV-2 protease, 3CLpro. Muralidharan et al. J. Biomol. Struct. Dyn., Apr 16 2020; https://doi.org/10.1080/07391102.2020.1752802
- Datasheet: view or download
- Applications:Approved drug (U.S.); in COVID-19 clinical trials, often in combination with Lopinavir and Ritonavir
Product Type:
Biochemicals & reagents
CAS Number:
7647-11-08
Range:
1) RW Sidwell et al. Antiviral Res. 1998 37:107 2) K McClellan and CM Perry Drugs 2001 61:263 3) W Li et al. Antimicrob. Agents Chemother. 1998 42:647
Limit of Detection:
410.4
Storage Temperature:
-20°C
Additional Information:
Oseltamivir is a potent viral neuraminidase inhibitor and a clinically useful treatment for influenzas A and B (1,2) and is a prodrug that is converted to the active acid in vivo (IC50 for active acid in vitro = 2 nM3).