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FLT-3-LG, mouse recombinant

Catalogue number:
GFM6-100
Size:
100 µg
Product is available in:
  • USA
  • Canada
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FMS-related Tyrosine Kinase 3 Ligand (FLT-3 Ligand) is a growth factor important for the proliferation of hematopoietic cells. FLT-3 Ligand binds to, and transmits signals through, the receptor tyrosine kinase known as FLT-3. FLT-3 Ligand promotes long-term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. Human FLT-3 Ligand can stimulate the proliferation of cells expressing murine FLT-3 receptors. Recombinant mouse FLT-3 Ligand is a non-glycosylated protein.

Product Type:

Peptides & proteins

Alternative Names:

FLt3 L, Fms-related tyrosine kinase 3 ligand

Storage Temperature:

-20°C

Additional Information:

NAME: FLT-3 Ligand; ACCESSION/UNIPROT#: P49772; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: OCI-AML5 cell proliferation with an acceptance criteria of 10 ng/mL (ED50), 1 x 10^5 units/mg.; #AA: 163; SEQUENCE: MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ