TGF-β3, mouse recombinant
The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-β isoforms (TGF-β1, -β2 and -β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant mouse TGF-β3 is a non-glycosylated, disulfide-linked homodimer.
Peptides & proteins
at 4°C
at least 12 months
NAME: Transforming Growth Factor beta 3; ACCESSION/UNIPROT#: P10600; EXPRESSION SYSTEM: E.coli; FORMAT: In solution, 10 mM acetic acid and 20% Ethanol at a concentration of 0.25 mg/mL.; TESTING: Inhibition of IL-4-induced HT-2 cell proliferation with an acceptance criteria of 1 ng/mL (ED50), 1.0 x 10^6 units/mg.; #AA: 226; SEQUENCE: MALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS