www.mayflowerbio.com
Sales & Support: 314-485-5210

*

GM-CSF, human recombinant

Catalogue number:
GFH8-5
Size:
5 µg
Product is available in:
  • USA
  • Canada
$75.00 Shipping is calculated in checkout

Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. GM-CSF receptors shows significant homologies with other receptors for hematopoietic growth factors, including IL-2 beta, IL-3, IL-6, IL-7, EPO and the Prolactin receptors. Recombinant Human GM-CSF is a single, non-glycosylated polypeptide chain.

Product Type:

Peptides & proteins

Alternative Names:

CSF-2. Pluripoietin-α, MGI1GM

Storage Temperature:

-20°C

Additional Information:

NAME: Granulocyte Macrophage Colony Stimulating Factor; ACCESSION/UNIPROT#: P04141; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate,pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: TF-1 cell proliferation with an acceptance criteria of 200 pg/mL (ED50), 5 x 10^6 units/mg.; #AA: 128; SEQUENCE: MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE