BMP-2, human recombinant
BMP-2 belongs to the bone-growth regulatory factors that are members of the transforming growth factor-beta (TGF-beta) superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. Recombinant Human Bone Morphogenetic protein-2 produced in E. coli is a homodimeric non-glycosylated protein.
Peptides & proteins
BMP-2A
-20°C
NAME: Bone Morphogenetic Protein-2; ACCESSION/UNIPROT#: P12643; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: Alkaline phosphatase activity induced in ATDC-5 cells with an acceptance criteria of 250 ng/mL (ED50), 4 x 10^3 units/mg.; #AA: 230; SEQUENCE: MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR