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Follistatin, human recombinant

Catalogue number:
GFH41-20
Size:
20 µg
Product is available in:
  • USA
  • Canada
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Follistatin is an autocrine acting protein that is expressed by many tissues, but at noteably higher levels in the ovary and skin. Follistatin functions to negatively regulate the signaling of a wide variety of TGF-beta family members (activin, BMPs, myostatin, GDF-11 and TGF-beta 1). Mechanistically, follistatin works as an antagonist by complexing with TGF-beta family members to prevent them from interacting with their signaling receptors. Recombinant human Follistatin is a non-glycosylated protein.

Product Type:

Peptides & proteins

Alternative Names:

FS, activin-binding protein, FSH-suppressing protein (FSP)

Storage Temperature:

-20°C

Additional Information:

NAME: Follistatin; ACCESSION/UNIPROT#: P19883; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50mM sodium chloride, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: Neutralization of human Activin A with an acceptance criteria of 200 ng/mL (ED50), 5.0 x 10^3 units/mg.; #AA: 289; SEQUENCE: MGNCWLRQAK NGRCQVLYKT ELSKEECCST GRLSTSWTEE DVNDNTLFKW MIFNGGAPNC IPCKETCENV DCGPGKKCRMNKKNKPRCVC APDCSNITWK GPVCGLDGKT YRNECALLKA RCKEQPELEV QYQGRCKKTC RDVFCPGSST CVVDQTNNAY CVTCNRICPEPASSEQYLCG NDGVTYSSAC HLRKATCLLG RSIGLAYEGK CIKAKSCEDI QCTGGKKCLW DFKVGRGRCS LCDELCPDSK SDEPVCASDNATYASECAMK EAACSSGVLL EVKHSGSCN