FLT-3-LG, human recombinant
This ligand binds to Fms-Like Tyrosine Kinase-3 (FLT-3). Human FLT-3 Ligand also stimulates the proliferation of cells expressing murine FLT-3 receptors. The effects of FLT-3 Ligand are synergized by coexpression of G-CSF, GM-CSF, M-CSF, IL-3 and SCF. FLT-3 ligand promotes long-term expansion and differentiation of human pro-B-cells in the presence of IL-7 or in combination of IL-7 and IL-3. Recombinant Human FLT-3 Ligand is a non-glycosylated, polypeptide chain.
Peptides & proteins
FLt3 L, Fms-related tyrosine kinase 3 ligand
-20°C
NAME: FLT-3 Ligand; ACCESSION/UNIPROT#: P49771; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: OCI-AML5 cell proliferation with an acceptance criteria of 10 ng/mL (ED50), 1 x 10^5 units/mg.; #AA: 155; SEQUENCE: MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT