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TGF-α, human recombinant

Catalogue number:
GFH209-50
Size:
50 µg
Product is available in:
  • USA
  • Canada
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Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family. TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. TGF-α functions as a mitogen to activate epithelial cell proliferation, growth, and differentiation. In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach disease. TGF-α is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells.

Product Type:

Peptides & proteins

Alternative Names:

Tumor growth factor alpha, TGF-alpha, EGF-like TGF, ETGF, TGFA, TGF type 1

Additional Information:

NAME: TGF-α; ACCESSION/UNIPROT#: P01135; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; #AA: 50; SEQUENCE: VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA