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PTK787

Catalogue number:
SM80-100
Size:
100 mg
Product is available in:
  • USA
  • Canada
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PTK787 is an inhibitor of VEGFR2/KDR, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4. PTK787 also inhibits Flk, c-Kit and PDGFR-β. PTK787 inhibits VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival. It shows the anti-proliferation effect by inhibiting thymidine incorporation induced by VEGF in HUVECs.

Product Type:

Peptides & proteins

CAS Number:

212141-51-0

Alternative Names:

Vatalanib, CGP-79787, ZK222584, N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine dihydrochloride