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Catalogue number:
50 mg
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IWP-2 is an inhibitor of Wnt processing and secretion. It appears that IWP inactivates Porcn function either by directly inhibiting the Porcn active site or by modulating the function of a Porcn regulator. IWP-2 promotes cardiomyocyte differentiation from human pluripotent stem cells (hPSC). This small molecule also suppresses self-renewal in mouse embryonic stem cells and supports their conversion to epiblast-like stem cells.

Product Type:

Peptides & proteins

CAS Number:


Alternative Names:

Inhibitor of WNT Production-2, N-​(6-​methyl-​2-​benzothiazolyl)-​2-​[(3,​4,​6,​7-​tetrahydro-​4-​oxo-​3-​phenylthieno[3,​2-​d]pyrimidin-​2-​yl)thio]-​acetamide


1) ten Berge, D., et al. 2011. Nat Cell Biol. 13(9): 1070-1075. PMID: 21841791; 2) Chen, B., et al. 2009. Nat Chem Biol. 5(2): 100-107. PMID: 19125156

Limit of Detection:


Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt