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Forskolin

Catalogue number:
SM18-100
Size:
100 mg
Product is available in:
  • USA
  • Canada
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Forskolin is a cAMP pathway activator, by activating adenylyl cyclase. Forskolin allows maintenance of human embryonic stem cells in a naive or ground state similar to mouse embryonic stem cells. Forskolin also enables chemical reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells, when combined with other small molecules. Forskolin is a vasodilator, which can help in controlling the cause of glaucoma and reduce urinary tract infections.

Product Type:

Peptides & proteins

CAS Number:

66575-29-9

Alternative Names:

Colforsin, Coleonol, [3R(3α,4aβ,5β,6β,6aα,10α,10aβ,10bα)]-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10apentamethyl-1H-naphtho[2,1-b]pyran-1-one

Range:

1) Seamon, K.B., et al. 1986. Adv Cyclic Nucleotide Protein Phosphorylation Res. 20: 1-150. PMID: 3028083; 2) Laurenza, A., et al. 1989. Trends pharmacol. Sci. 10: 442-447. PMID: 2692256; 3) De Souza, N.J., et al. 1983. Med Res Rev. 3: 201-219. PMID: 6345959; 4) Hanna, J., et al. 2010. Proc Natl Acad Sci USA. 107(20): 9222-9227. PMID: 20442331; 5) Hou, P., et al. 2013. Science. 341(6146): 651-654. PMID: 23868920

Limit of Detection:

410.5

Storage Temperature:

-20°C. Keep away from direct sunlight.

Shelf Life:

12 months from receipt