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IL-15 (animal free), mouse recombinant

IL-15 (animal free), mouse recombinant
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Size: 10 µg
POA
 
Catalogue number:
GFM007AF-10
Name:
IL-15 (animal free), mouse recombinant
Supplier:
Availability:
This product is no longer available to order.

Interleukin-15 (IL-15) is a pleiotropic pro-inflammatory cytokine that is expressed in several inflammatory disorders, including rheumatoid arthritis, psoriasis and pulmonary inflammatory diseases. IL-15 promotes activation of T cells, neutrophils and macrophages, and is critical to dendritic cell function in several model systems. Recent emerging data suggest that IL-15 may serve as a useful therapeutic target across a range of disease states. Advances in the past year highlight the beneficial effect of IL-15 neutralization in models of psoriasis and diabetes. Further evidence for IL-15 expression and effector function has emerged across a range of rheumatic disorders, including juvenile inflammatory arthritis, rheumatoid arthritis and Kawasaki disease. IL-15 is a gamma-common cytokine, which plays an important role in the development, survival and proliferation of NK, NK T and CD8+ T cells. Recombinant Mouse IL-15 is a single, non-glycosylated polypeptide chain.

Product Type:
Peptides & proteins
Alternative Names:
IL-T
Storage Temp:
-20°C
Molecular Weight:
13.4 kDa
Specifications:
PURITY (MIN.): ≥95
Additional Information:
Produced using animal free raw components and processes, in a non-mammalian system. Ideal for researchers concerned about the risks and effects of contaminating viruses, prions and trace growth factors from FBS and animal-derived ingredients used in standard recombinant protein production techniques. Endotoxin levels are less than 1.0 EU per ug protein via LAL. Bioactivity is comparable to recombinant protein produced in traditional techniques.