Afatinib
Supplier:
Catalogue number:
10-4510-01
Size:
10 mg
Product is available in:
EGFR and HER2 inhibitor / Afatinib is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50 = 0.5 nM) and HER2 (IC50 = 14 nM).
Product Type:
Biochemicals & reagents
CAS Number:
850140-72-6
Alternative Names:
BIBW2992
Reference:
1) Li et al. (2008), BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models; Oncogene 27 4702
Storage Temperature:
-20°C
Additional Information:
TARGET: Kinase -- PATHWAY: EGF -- DISEASE AREA: Cancer