GW-441756
Supplier:
Catalogue number:
10-1023-02
Size:
25 mg
Product is available in:
NGFR kinase inhibitor / GW-441756 is a potent and selective TrkA kinase inhibitor (IC50 = 2 nM).
Product Type:
Biochemicals & reagents
CAS Number:
504433-23-2
Reference:
1) Wood et al (2004) Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles. Bioorg.Med.Chem.Lett. 14 953 2) Takemoto et al. (2015) Neuroprotection elicited by nerve growth factor and brain-derived neurotrophic factor released from astrocytes in response to methyl mercury; Environ. Toxicol. Pharmacol. 40 199 [Focus Citation]
Storage Temperature:
RT
Additional Information:
TARGET: Kinase -- PATHWAY: Proliferation -- RESEARCH AREA: Neuroscience -- DISEASE AREA: Cancer