LDC1267
Supplier:
Catalogue number:
10-4420-01
Size:
5 mg
Product is available in:
Selective inhibitor of TAM kinases / LDC1267 is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.
Product Type:
Biochemicals & reagents
CAS Number:
1361030-48-9
Reference:
1) Paolino et al. (2014), The E3 Ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells; Nature 507 508
Storage Temperature:
-20°C
Additional Information:
TARGET: Kinase -- RESEARCH AREA: Immunology -- DISEASE AREA: Cancer