SBI-0206965
Supplier:
Catalogue number:
10-1623-02
Size:
25 mg
Product is available in:
ULK1 inhibitor / A potent and selective inhibitor of the autophagy kinase ULK-1, IC50=108 and 711 nM for ULK1 and 2 respectively.1 Suppresses autophagy induced by mTOR inhibitors and thus synergizes with mTOR inhibitors to induce apoptosis and cell death in tumor cells.1
Product Type:
Biochemicals & reagents
CAS Number:
1884220-36-3
Reference:
1) Egan et al. (2015), Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates; Mol. Cell, 59 285
Storage Temperature:
-20°C
Additional Information:
TARGET: Kinase -- PATHWAY: mTOR; Autophagy; Apoptosis inducer -- RESEARCH AREA: Cell death -- DISEASE AREA: Cancer