Glumetinib
Supplier:
Catalogue number:
10-4690-02
Size:
25 mg
Product is available in:
Highly selective c-Met inhibitor / Highly selective (2400-fold selectivity against a panel of 312 kinases) and potent (IC50 = 0.42 nM) inhibitor of c-Met kinase. It induced tumor regression in MET-driven CDX (MKN-45, SNU-5, EBC-1) and PDX (4 NSCLC, 5 HCC) tumor models.
Product Type:
Biochemicals & reagents
CAS Number:
1642581-63-2
Alternative Names:
SCC244
Reference:
Ai et al. (2018), Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models; Cancer Res., 17 751
Storage Temperature:
-20°C
Additional Information:
TARGET: Kinase -- PATHWAY: Proliferation -- RESEARCH AREA: Angiogenesis -- DISEASE AREA: Cancer