Optovin
Supplier:
Catalogue number:
10-1456-02
Size:
25 mg
Product is available in:
TRPA1 channel activator / Reversible, photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM) and mice, in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1
Product Type:
Biochemicals & reagents
CAS Number:
348575-88-2
Reference:
1) Kokel et al. (2013), Photochemical activation of TRPA1 channels in neurons and animals; Nat. Chem. Biol., 9 257
Storage Temperature:
-20°C
Additional Information:
TARGET: Ion channel -- PATHWAY: Cation channel